As a fertility doctor, I often see couples who have gone through one of the most heartbreaking experiences: recurrent pregnancy loss (RPL). It’s emotionally draining, and often, it leaves patients searching for answers. At Rainbow Hospitals in Hyderabad, we approach every case with compassion, thorough evaluation, and a clear plan — because we know how important it is to support couples through this sensitive journey.

What is Recurrent Pregnancy Loss?

We define recurrent pregnancy loss as two or more consecutive pregnancy losses before 24 weeks of gestation. A single miscarriage can happen to anyone — in fact, around 10–15% of all pregnancies end in early loss. But when it happens more than once, it’s important to look deeper.

Patients often ask me, “Why is this happening to me?” The answer is: there are multiple possible causes — and fortunately, many of them can be identified and treated.

What Causes Recurrent Pregnancy Loss?

Around 50% of RPL cases have an identifiable cause, while the other 50% remain unexplained. Some of the most common causes include:

• Genetic issues in the embryo – Often due to chromosomal abnormalities, especially in early miscarriages.
• Anatomical factors – Conditions like a septate uterus, fibroids, or intrauterine adhesions that interfere with implantation.
• Endocrine disorders – Uncontrolled thyroid issues, PCOS, or diabetes can increase the risk.
• Autoimmune conditions – Issues like antiphospholipid syndrome (APLA) or lupus may lead to the body rejecting the pregnancy.
• Blood clotting disorders (thrombophilias) – These can prevent adequate blood flow to the developing embryo.
• Sperm DNA fragmentation – A less commonly discussed but important male factor that may affect embryo quality.

And yes, age is a key factor — especially maternal age. Women above 35 have a higher chance of egg-related genetic anomalies. That’s why early evaluation and timely intervention are crucial.

How We Evaluate Recurrent Pregnancy Loss

At Rainbow Hospitals, we take a comprehensive, step-by-step approach. This includes:

• Detailed medical history and physical exam
• Ultrasound and hysteroscopy to check the uterus
• Karyotyping (genetic testing) for both partners
• Autoimmune and thrombophilia screening
• Hormonal evaluation
• Semen analysis and DNA fragmentation testing for the male partner

Most of these tests can be done in a single location, and within 3 to 4 weeks, we usually have a complete picture.

What Treatments Are Available?

If we identify a treatable cause, we personalize the treatment:

• Surgical correction of uterine anomalies like septum or fibroids
• Blood thinners and aspirin for autoimmune or clotting issues
• Lifestyle guidance, including weight loss, stress management, and addressing smoking or alcohol
• IVF with preimplantation genetic testing (PGT) in case of genetic concerns
• Donor egg or sperm in rare cases with significant abnormalities

If no clear cause is found, we counsel the couple and support them emotionally. The good news is, even without a specific diagnosis, many couples go on to have healthy pregnancies.

A Final Word

Recurrent pregnancy loss is emotionally heavy, but you're not alone — and you're not without hope. With the right evaluation and expert care, successful outcomes are absolutely possible.

If you or someone you know is dealing with this, don’t wait. Reach out to a fertility specialist in Hyderabad. At Rainbow Hospitals, I’m here to listen, evaluate, and help you find the way forward — with science, support, and heartfelt care.